Does Probiotic Yeast Act as Antigenotoxin?**
نویسندگان
چکیده
The effect of probiotic yeast Saccharomyces boulardii on genotoxicity induced by the well-known mutagen 4-nitroquinoline-N-oxide (4-NQO), as well as antibacterial (furazolidone) and antibiotic (nalidixic acid) drugs, has been studied using the short-term bacterial assay, SOS chromotest, with Escherichia coli PQ 37 as the test organism. It has been shown that S. boulardii possesses antigenotoxic activity, revealed by SOS chromotest, when coincubated with these genotoxins. A weaker antigenotoxic activity against the same compounds was observed with S. carlsbergensis, too.
منابع مشابه
Saccharomyces cerevisiae var. boulardii as a eukaryotic probiotic and its therapeutic functions
Fuller, in 1989, described probiotic microorganisms as “a live microbial feed supplement,which beneficially affects the host animal, by improving its intestinal microbial balance”.Saccharomyces cerevisiae var. boulardii (S.boulardii) is an accurate probiotic yeast idol.The detection and budding of S.boulardiiis firmly related to the impression of healthinessto promote microorganisms from foodst...
متن کاملSaccharomyces boulardii and Candida albicans experimental colonization of the murine gut.
Saccharomyces boulardii has been and continues to be extensively used as a probiotic, with only rare associations with fungemia. This study evaluated the virulence of this yeast when given as a probiotic, and its role in preventing gastrointestinal (GI) colonization by Candida. Adult male Crl:CD1 (ICR) BR mice were given S. boulardii orally in three different doses or normal saline for 14 days....
متن کاملYeast Modulation of Human Dendritic Cell Cytokine Secretion: An In Vitro Study
Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. The concept of individual microorganisms influencing the makeup of T cell subsets via interactions with intestinal dendritic cells (DCs) appears to constitute the foundation for immunoregulatory effects of probiotics, and several studies have reported probiotic strains resulting i...
متن کاملGleaning evolutionary insights from the genome sequence of a probiotic yeast Saccharomyces boulardii
BACKGROUND The yeast Saccharomyces boulardii is used worldwide as a probiotic to alleviate the effects of several gastrointestinal diseases and control antibiotics-associated diarrhea. While many studies report the probiotic effects of S. boulardii, no genome information for this yeast is currently available in the public domain. RESULTS We report the 11.4 Mbp draft genome of this probiotic y...
متن کاملتأثیر تغذیه با آهن و مخمر تک سلولی غنی شده با کروم زیستی بر فاکتورهای خونی در رت نر دیابتی شده با استرپتوزوتوسین
Background: Chrome is regarded as an essential nutrient required for glucose and lipid metabolism, specifically in diabetic patients. Converting mineral form of chromium to organic as well as increasing its absorption seem to have more fruitful therapeutic effects due to the synergistic effect of these two anti-diabetes compounds(yeast and chromium). Therefore, the present study aimed to evalu...
متن کامل